Publications

Read more about wound debridement and healing.

A strong body of literature has been published in scientific journals and presented at conferences on OPAL A, the OPAL Process and the positive impact of OPAL A in the treatment of hard to treat wounds and ulcers.  A compilation of publications and posters is summarised below.

Date Title of publication or poster Publication and Author/s
July 2016 Retaining in-gel zymographic activity of cysteine proteases via a cysteine-supplemented running buffer

Sreekanth Vootukuri Reddy
Mike P. Philpott
Giuseppe Trigiante

May 2014 Optiderma OPAL A. For the preventative treatment and management of chronic wounds for Aged Care providers. A model for change

Presentation at the Australian Wound Management Association conference

Baldock M
May 2014 Randomised, Placebo-controlled Study of OPAL A for the Treatment of Chronic Venous and Pressure Ulcers

Poster presentation at the Australasian Wound & Tissue Repair Society and Australian Wound Management Association conferences

Woodward M, Woolley M, Richardson M
May 2014

Cysteine Proteases May Play a Role in the Wound Healing

Properties of OPAL A

Poster presentation at the Australasian Wound & Tissue Repair Society and Australian Wound Management Association conferences

Philpott M, Rzechorzek N, Mitchell G and Woodward M
May 2014 Enzymatic Debridement: A failed promise, or hope for the future?

Presentation at the Australian Wound Management Association conference

Nowicki J, Siviour A
June 2013 Best practice skin care management in lymphoedema

Jake Nowicki

Alex Siviour

December 2011 Effect of the novel wound healing agent, OPAL A on leukotriene B4 production in human neutrophils and 5-lipoxygenase activity

Wound & Practice Research - Journal of the Australian Wound management Association

Russell FD, Windegger T, Hamilton KD & Cheetham NWH
December 2011 Clinical observations supporting a vasodilatory effect of the modified papaya extract OPAL001

Wound & Practice Research - Journal of the Australian Wound management Association

Mitchell GK
December 2011 Treatment of a sacral pressure ulcer and extensive hyperkeratosis with OPAL A filtrate and cream

Wound & Practice Research - Journal of the Australian Wound management Association

Baldwin C and Bonham S
May 2010 Potential treatment for the hard to heal

Hospital & Aged Care

March 2010 The treatment of chronic pressure ulcers on the foot with OPAL A

Presentation to the Australian Wound Management Association conference

Bonham S, Baldwin C, Tozer L
March 2010 Clinical observations and physiological data supporting a vascular response as a mechanism of the novel wound-healing agent, OPAL A

G. Mitchell
T. Windegger
F.D. Russell

March 2010 Inhibition of 5-lipoxygenase activity by The novel wound-healing agent, OPAL A

Fraser D. Russell
Tanja Windegger
Norman W.H. Cheetham
Geoffrey Mitch

March 2010 OPAL Products - Treatment of Partial Thickness Burns

Dr Lyn Tozer
Prof. Geoff Mitchell

March 2010 Case Series: Treatment of Chronic Wounds with Alkalised Fruit Extract

G. Mitchell
LMR Tozer

January 2010 Proof of concept for wound care trial

Hospital & Aged Care

May 2009 The treatment of vascular ulcers with alkalised fruit extract

Geoffrey Mitchell
Michael Woodward

May 2008 Alkalised fruit extract as a potential treatment for chronic ulcers – a case series

Presentation at the Australian Wound Management Association conference

Mitchell G, McArthur T, Hollerback K, Richardson M
May 2008 The use of OPAL001 filtrate and cream in the treatment of chronic pressure ulcers

Wound Practice & Research

Graves N & Ashby AE
May 2008 Clinical efficacy of OPAL001 and OPAL A in the treatment of a variety of different ulcer types

European Wound Management Association conference in Helsinki

July 2005 The use of OPAL A Cream and Lotion

Quadriplegic Centre, Western Australia

Piercey C, Knight R

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